Prevention of lipofuscin development in neurons by anti-oxidants

  title={Prevention of lipofuscin development in neurons by anti-oxidants},
  author={Paris Constantinides and Martha R Harkey and Daniel McLaury},
  journal={Virchows Archiv A},
It was documented that ageing is associated with a progressive and highly significant proliferation of the total number of light microscopically visible lipofuscin granules in the grey substance of sections of the cervical spinal cord of Balb/c mice. The mean total numbers (±standard errors) of lipofuscin granules in standard sections of the glutaraldehyde-osmium fixed, epon embedded spinal cords that were examined with a phase contrast light microscope in 1 week, 1 month, 8 months and 18… CONTINUE READING


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