Prevention of intracranial hypertension during laryngoscopy and endotracheal intubation. Use of a second dose of thiopentone.

@article{Unni1984PreventionOI,
  title={Prevention of intracranial hypertension during laryngoscopy and endotracheal intubation. Use of a second dose of thiopentone.},
  author={Vinod K. Unni and Robert A. Johnston and H S Young and R. J. Mcbride},
  journal={British journal of anaesthesia},
  year={1984},
  volume={56 11},
  pages={
          1219-23
        }
}
In nine patients, with preoperative ICP monitoring, anaesthesia was induced with thiopentone 5 mg kg-1 given over 1 min, followed by pancuronium 0.1 mg kg-1. After manual hyperventilation with nitrous oxide and oxygen for 3 min they were given thiopentone 2.5 mg kg-1 over 30 s (phase 1); 30 s later laryngoscopy was performed and topical analgesia administered to the larynx. Endotracheal intubation was performed 1 min after spraying the cords (phase 2). The measurements continued for a further 5… Expand
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