Prevention of intimal hyperplasia employing the cavitary two-layer method in allogeneic rat heart transplantation.

BACKGROUND The development of graft arteriosclerosis is a significant contributor to chronic rejection in organ transplant recipients. The purpose of the present study was to establish whether or not the cavitary two-layer method can prevent graft arteriosclerosis after rat heart transplantation. METHODS F-344 rats served as donors to Lewis recipients… CONTINUE READING