Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses.

@article{Gustilo1976PreventionOI,
  title={Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses.},
  author={Ramon B. Gustilo and Jane Anderson},
  journal={The Journal of bone and joint surgery. American volume},
  year={1976},
  volume={58 4},
  pages={
          453-8
        }
}
  • R. Gustilo, J. Anderson
  • Published 1 April 2002
  • Medicine
  • The Journal of bone and joint surgery. American volume
In 673 open fractures of long bones (tibia and fibula, femur, radius and ulna, and humerus) treated from 1955 to 1968 at Hennepin County Medical Center, Minneapolis, Minnesota, and analyzed retrospectively, the infection rate was 12 per cent from 1955 to 1960 and 5 per cent from 1961 to 1968. In a prospective study from 1969 to 1973, 352 patients were managed as follows: débridement and copious irrigation, primary closure for Type I and II fractures and secondary closure for Type III fractures… 
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