Prevention of hereditary cardiomyopathy in the Syrian hamster with chronic verapamil therapy.

@article{Factor1988PreventionOH,
  title={Prevention of hereditary cardiomyopathy in the Syrian hamster with chronic verapamil therapy.},
  author={Stephen M. Factor and Sang Ho Cho and James Scheuer and Edmund H. Sonnenblick and A. M. Malhotra},
  journal={Journal of the American College of Cardiology},
  year={1988},
  volume={12 6},
  pages={1599-604}
}
The cardiomyopathic Syrian hamster develops genetically determined cardiac necrosis that invariably leads to premature death from congestive heart failure or arrhythmia. This hamster is a valuable model of human disease because it has many features in common with clinical dilated, congestive cardiomyopathy. Previous studies have shown that therapy for several weeks with the calcium channel blocking drug verapamil or the alpha-1 adrenoceptor blocking drug prazosin can prevent myocardial necrosis… CONTINUE READING
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