Prevention of hepatitis B virus recurrence after liver transplantation in cirrhotic patients treated with lamivudine and passive immunoprophylaxis.
@article{Marzano2001PreventionOH, title={Prevention of hepatitis B virus recurrence after liver transplantation in cirrhotic patients treated with lamivudine and passive immunoprophylaxis.}, author={Alfredo Marzano and Mauro Salizzoni and Wilma Debernardi-Venon and Antonella Smedile and Alessandro Franchello and Alessia Ciancio and Elena Gentilcore and Paolo Piantino and Anna Maria Barbui and Ezio David and Francesco Negro and Mario Rizzetto}, journal={Journal of hepatology}, year={2001}, volume={34 6}, pages={ 903-10 } }
BACKGROUND/AIMS
Treatment with hepatitis B virus immune globulins (HBIG) or lamivudine has reduced the rate of hepatitis B recurrence after liver transplantation to approximately 50%.
METHODS
To further decrease hepatitis B recurrence, 33 hepatitis B virus (HBV)-related cirrhotic patients were treated with lamivudine before liver transplantation and with lamivudine together with low-dose HBIG (46 500 IU the first month followed by 5,000 lU/monthly) after surgery.
RESULTS
While on lamivudine… CONTINUE READING
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