Prevention of gastrulation but not neurulation by antibodies to fibronectin in amphibian embryos

@article{Boucaut1984PreventionOG,
  title={Prevention of gastrulation but not neurulation by antibodies to fibronectin in amphibian embryos},
  author={Jean Claude Boucaut and Thierry Darrib{\`e}re and Habib Boulekbache and Jean Paul Thiery},
  journal={Nature},
  year={1984},
  volume={307},
  pages={364-367}
}
Gastrulation and formation of the neural plate are major steps in early vertebrate embryogenesis. Although morphogenetic movements leading to the formation of the primary germ layers have been extensively described1–3, the mechanisms governing migration of mesodermal cells and their interactions with ectoderm remain ill-defined. A large body of evidence indicates that fibronectin (FN), a high molecular weight cell-surface-associated glycoprotein, promotes cell adhesion and cell migration… CONTINUE READING

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