Prevention of free radical-induced myocardial injury by allopurinol. Experimental study in cardiac preservation and transplantation.

@article{Bando1988PreventionOF,
  title={Prevention of free radical-induced myocardial injury by allopurinol. Experimental study in cardiac preservation and transplantation.},
  author={Koichi Bando and Mamoru Tago and Shigeru Teramoto},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={1988},
  volume={95 3},
  pages={465-73}
}
To determine the role of free radical-induced injury during heart preservation and transplantation, we harvested hearts from 28 mongrel dogs (12.5 to 16.5 kg), divided them into four groups, and orthotopically transplanted them. A group of seven hearts were orthotopically transplanted immediately after excision (group A). A second group of seven animals… CONTINUE READING