Prevention of experimental proliferative vitreoretinopathy with a biodegradable intravitreal drug delivery system of all-trans retinoic acid.

Abstract

PURPOSE To evaluate the antiproliferative effect of an all-trans retinoic acid (at-RA) drug delivery system (DDS) on experimental proliferative vitreoretinopathy (PVR). METHODS PVR was induced in rabbits with core vitrectomy and fibroblast injection. The DDS containing 420 microg, 650 microg, and 1,070 microg of at-RA was implanted into the vitreous of… (More)

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@article{Dong2006PreventionOE, title={Prevention of experimental proliferative vitreoretinopathy with a biodegradable intravitreal drug delivery system of all-trans retinoic acid.}, author={Xiaoguang Dong and Nan Chen and Lixin Xie and Shenguo Wang}, journal={Retina}, year={2006}, volume={26 2}, pages={210-3} }