Prevention of epilepsy after head trauma: do we need new drugs or a new approach?

  title={Prevention of epilepsy after head trauma: do we need new drugs or a new approach?},
  author={Larry S. Benardo},
  volume={44 s10},
Annually in the U.S. about 500,000 head injuries are severe enough to require hospitalization. Past studies of severe head trauma estimate the risk of late seizures, which are synonymous with epilepsy, to be from 26 to 53%. Furthermore, head trauma accounts for 5% of all epilepsy cases and 20% of symptomatic epilepsy. Although potentially preventable, no effective prophylaxis for posttraumatic epilepsy currently exists. Prior attempts to prevent posttraumatic epileptogenesis used various… CONTINUE READING


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