Prevention of epidural fibrosis in rats by local or systemic administration of citicoline.

Abstract

AIM The objective of this study was to investigate the effect of citicoline administration on epidural fibrosis which is a frequent complication of lumbar disc surgery with no effective treatment or preventive surgical technique. MATERIAL AND METHODS Sixty Sprague-Dawley female rats undergoing L4-5 right hemilaminotomy and annular fenestration were… (More)
DOI: 10.5137/1019-5149.JTN.6008-12.0

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