Prevention of endothelin-1-induced increases in blood pressure: role of endogenous CGRP.

@article{Wang2004PreventionOE,
  title={Prevention of endothelin-1-induced increases in blood pressure: role of endogenous CGRP.},
  author={Youping Wang and Donna H. Wang},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2004},
  volume={287 4},
  pages={H1868-74}
}
To determine the role of endothelin-1 (ET-1) and its receptors in the regulation of calcitonin gene-related peptide (CGRP) release, male Wistar rats were divided into six groups and subjected to the following treatments for 1 wk with or without ABT-627 (an ET(A) receptor antagonist, 5 mg.kg(-1).day(-1) in drinking water) or A-192621 (an ET(B)-receptor antagonist, 30 mg.kg(-1).day(-1) by oral gavage): control (Con), ET-1 (5 ng.kg(-1).min(-1) iv), Con + ABT-627, Con + A-192621, ET-1 + ABT-627… CONTINUE READING
28 Citations
37 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 37 references

An overview of endothelin signaling in the cardiac myocyte

  • SC Supowit, CV Ramana, KN Westlund, DJ DiPette
  • J Mol Cell Cardiol
  • 2003

Similar Papers

Loading similar papers…