Prevention of emesis from multiple-day and high-dose chemotherapy regimens.

  title={Prevention of emesis from multiple-day and high-dose chemotherapy regimens.},
  author={Rudolph M. Navari},
  journal={Journal of the National Comprehensive Cancer Network : JNCCN},
  volume={5 1},
The prevention of chemotherapy-induced nausea and vomiting (CINV) has improved significantly with the introduction of the 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists combined with dexamethasone. Most studies have reported on patients undergoing single-day highly or moderately emetogenic chemotherapy. There have been fewer studies and much less success in preventing CINV in patients undergoing multiple-day chemotherapy or high-dose chemotherapy with stem cell transplant. Current… CONTINUE READING
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