Prevention of dopaminergic neurotoxicity by targeting nitric oxide and peroxynitrite: implications for the prevention of methamphetamine-induced neurotoxic damage.

Abstract

Methamphetamine (METH) is a neurotoxic psychostimulant that produces catecholaminergic brain damage by producing oxidative stress and free radical generation. The role of oxygen and nitrogen radicals is well documented as a cause of METH-induced neurotoxic damage. In this study, we have obtained evidence that METH-induced neurotoxicity is the resultant of… (More)

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Cite this paper

@article{Imam2000PreventionOD, title={Prevention of dopaminergic neurotoxicity by targeting nitric oxide and peroxynitrite: implications for the prevention of methamphetamine-induced neurotoxic damage.}, author={Saheed Imam and Fakir M Amirul Islam and Yoseph Itzhak and William Slikker and S Fahd Ali}, journal={Annals of the New York Academy of Sciences}, year={2000}, volume={914}, pages={157-71} }