Prevention of diet-induced obesity by dietary isomerized hop extract containing isohumulones, in rodents

@article{Yajima2005PreventionOD,
  title={Prevention of diet-induced obesity by dietary isomerized hop extract containing isohumulones, in rodents},
  author={H. Yajima and T. Noguchi and E. Ikeshima and M. Shiraki and T. Kanaya and N. Tsuboyama-Kasaoka and O. Ezaki and S. Oikawa and K. Kondo},
  journal={International Journal of Obesity},
  year={2005},
  volume={29},
  pages={991-997}
}
OBJECTIVE:Isomerized hop extract (IHE), which consists mainly of isohumulones and is required in the beer brewing process, was investigated for its effects on diet-induced obesity in two strains of mice.DESIGN:C57BL/6N and KK-Ay mice were fed a standard or high-fat diet containing IHE and their body and tissue weights were measured at various time points. Oral glucose tolerance tests (OGTT) and insulin tolerance tests (ITT) were carried out in high-fat diet-fed C57BL/6N mice. The effects of IHE… Expand
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