Prevention of deep vein thrombosis after hip replacement--comparison between two low-molecular heparins, tinzaparin and enoxaparin.

@article{Plans1999PreventionOD,
  title={Prevention of deep vein thrombosis after hip replacement--comparison between two low-molecular heparins, tinzaparin and enoxaparin.},
  author={Andr{\'e} Plan{\`e}s and Meyer Michel Samama and Anthie W A Lensing and Harry Roger B{\"u}ller and Jessica Barr{\'e} and Nicole Vochelle and Bernadette Beau},
  journal={Thrombosis and haemostasis},
  year={1999},
  volume={81 1},
  pages={22-5}
}
Consecutive patients undergoing total hip replacement in 43 centres were randomly assigned to receive blindly either enoxaparin (40 mg) or tinzaparin (4,500 anti-Factor IU Xa), as once daily subcutaneous injections. The first injection was administered 12 h preoperatively. Efficacy was assessed by bilateral venography performed 12-14 days postoperatively. Efficacy and safety were blindly and centrally adjudicated. Among the 499 patients included, 440 had a venogram. The total incidence of DVTs… CONTINUE READING

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