Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial

@article{Sever2003PreventionOC,
  title={Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial},
  author={P. Sever and B. Dahlöf and N. Poulter and H. Wedel and for the Ascot investigators},
  journal={The Lancet},
  year={2003},
  volume={361},
  pages={1149-1158}
}
  • P. Sever, B. Dahlöf, +2 authors for the Ascot investigators
  • Published 2003
  • Medicine
  • The Lancet
  • BACKGROUND The lowering of cholesterol concentrations in individuals at high risk of cardiovascular disease improves outcome. No study, however, has assessed benefits of cholesterol lowering in the primary prevention of coronary heart disease (CHD) in hypertensive patients who are not conventionally deemed dyslipidaemic. METHODS Of 19342 hypertensive patients (aged 40-79 years with at least three other cardiovascular risk factors) randomised to one of two antihypertensive regimens in the… CONTINUE READING
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