Prevention of citrate reactions during therapeutic plasma exchange by constant infusion of calcium gluconate with the return fluid.

@article{Weinstein1996PreventionOC,
  title={Prevention of citrate reactions during therapeutic plasma exchange by constant infusion of calcium gluconate with the return fluid.},
  author={Robert Weinstein},
  journal={Journal of clinical apheresis},
  year={1996},
  volume={11 4},
  pages={204-10}
}
We have examined the effectiveness of intravenous calcium gluconate infusion in the prevention of citrate reactions during therapeutic plasma exchange. Over 3 years, 636 procedures were performed on 90 patients, mostly for treatment of neurological disorders. Return fluid consisted of 4-5% human serum albumin in 0.9% NaCl. Anticoagulant ACD-A was used at a starting ratio of 1:16. Whole blood flow rates were 70-80 ml/min. Treatments were divided into three groups for management of citrate… CONTINUE READING
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