Prevention of cervical cancer through papillomavirus vaccination

  title={Prevention of cervical cancer through papillomavirus vaccination},
  author={Ian H Frazer},
  journal={Nature Reviews Immunology},
A subset of human papillomaviruses (HPVs) promote anogenital malignancy, including cervical cancer, and prevention and treatment strategies that reflect the causal role of HPV are being developed. Vaccines based on HPV virus-like particles induce genotype-specific virus-neutralizing antibody and prevent infection with HPV. Persistent papillomavirus infection is required for the development of papillomavirus-associated cancer and, therefore, therapeutic vaccines are being developed to eliminate… CONTINUE READING