Prevention of bone loss in renal transplant recipients: a prospective, randomized trial of intravenous pamidronate.

@article{Coco2003PreventionOB,
  title={Prevention of bone loss in renal transplant recipients: a prospective, randomized trial of intravenous pamidronate.},
  author={Maria Coco and Daniel G Glicklich and Marie Claude Faugere and Larry Burris and Istvan Bognar and Peter Durkin and Vivian A. Tellis and Stuart Greenstein and Richard S Schechner and Katherine W Figueroa and Patricia McDonough and Guodong Wang and Hartmut H. Malluche},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2003},
  volume={14 10},
  pages={2669-76}
}
Renal transplant recipients are at risk of developing bone abnormalities that result in bone loss and bone fractures. These are related to underlying renal osteodystrophy, hypophosphatemia, and immunosuppressive treatment regimen. Although bisphosphonates are useful in ameliorating bone mineral loss after transplantation, it is not known whether their use in renal transplant patients leads to excessive suppression of bone turnover and increased incidence of adynamic bone disease. A randomized… CONTINUE READING

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