Prevention of an increase in plasma cortisol during hypoglycemia preserves subsequent counterregulatory responses.

@article{Davis1997PreventionOA,
  title={Prevention of an increase in plasma cortisol during hypoglycemia preserves subsequent counterregulatory responses.},
  author={Stephen Neil Davis and Clyde Shavers and Bruce Davis and Fernando Costa},
  journal={The Journal of clinical investigation},
  year={1997},
  volume={100 2},
  pages={429-38}
}
The aim of this study was to determine whether preventing increases in plasma cortisol during antecedent hypoglycemia preserves autonomic nervous system counterregulatory responses during subsequent hypoglycemia. Experiments were carried out on 15 (8 male/7 female) healthy, overnight-fasted subjects and 8 (4 male/4 female) age- and weight-matched patients with primary adrenocortical failure. 5 d before a study, patients had their usual glucocorticoid therapy replaced with a continuous… CONTINUE READING
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