Prevention of amlodipine absorption by activated charcoal: effect of delay in charcoal administration.

@article{Laine1997PreventionOA,
  title={Prevention of amlodipine absorption by activated charcoal: effect of delay in charcoal administration.},
  author={Kari Laine and Kari T. Kivist{\"o} and Into Laakso and Pertti J Neuvonen},
  journal={British journal of clinical pharmacology},
  year={1997},
  volume={43 1},
  pages={29-33}
}
AIMS The purpose of this study was to investigate the effect of activated charcoal on the absorption of amlodipine, with special reference to delayed charcoal administration. METHODS Thirty-two healthy volunteers, eight subjects in four parallel groups, ingested 10 mg of amlodipine on an empty stomach. Activated charcoal (25 g in 300 ml of water) was ingested either immediately afterwards or 2 h or 6 h after amlodipine, or amlodipine was ingested with 300 ml of water only (control). Plasma… CONTINUE READING