Prevention of Nausea and Vomiting with Tandospirone in Adults After Tympanoplasty

@article{Oshima2002PreventionON,
  title={Prevention of Nausea and Vomiting with Tandospirone in Adults After Tympanoplasty},
  author={Tsutomu Oshima and Yoshiko Kasuya and Yasuhisa Okumura and Etsuji Terazawa and Shuji Dohi},
  journal={Anesthesia \& Analgesia},
  year={2002},
  volume={95},
  pages={1442-1445}
}
We have hypothesized that the 5-hydroxytrypta-mine-1A receptor agonist tandospirone reduces postoperative nausea and vomiting (PONV). In a double-blinded, randomized design, 3 groups of 30 patients each received 1 of the following oral medications 90 min before arrival in the operating room, together with famotidine 20 mg: 1) placebo (P group), 2) tandospirone 10 mg (T10 group), or 3) tandospirone 30 mg (T30 group). Standard anesthetic regimens and techniques were applied for all patients. All… 

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