Prevention of MRSA pneumonia by oral vancomycin decontamination: a randomised trial.

@article{Silvestri2004PreventionOM,
  title={Prevention of MRSA pneumonia by oral vancomycin decontamination: a randomised trial.},
  author={Luciano Silvestri and Hendrick K. F. van Saene and Marco Milanese and Francesco Fontana and Dario Gregori and Luisa Oblach and Nicola Piacente and Miranda Blazic},
  journal={The European respiratory journal},
  year={2004},
  volume={23 6},
  pages={921-6}
}
This study was undertaken to assess whether oropharyngeal vancomycin may control oropharyngeal carriage and lower airway infection due to methicillin-resistant Staphylococcus aureus (MRSA) acquired in the intensive care unit (ICU). Secondary endpoints were the emergence of vancomycin-resistant enterococci, vancomycin-intermediate S. aureus and vancomycin consumption. A total of 84 patients, admitted to a medical/surgical ICU and mechanically ventilated for >72 h, were randomly assigned to… CONTINUE READING

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