Prevention of Group B Streptococcal Early-Onset Disease in Newborns: ACOG Committee Opinion, Number 782.

@article{2019PreventionOG,
  title={Prevention of Group B Streptococcal Early-Onset Disease in Newborns: ACOG Committee Opinion, Number 782.},
  author={},
  journal={Obstetrics and gynecology},
  year={2019},
  volume={134 1},
  pages={
          e19-e40
        }
}
  • Published 2019
  • Medicine
  • Obstetrics and gynecology
Group B streptococcus (GBS) is the leading cause of newborn infection. The primary risk factor for neonatal GBS early-onset disease (EOD) is maternal colonization of the genitourinary and gastrointestinal tracts. Approximately 50% of women who are colonized with GBS will transmit the bacteria to their newborns. Vertical transmission usually occurs during labor or after rupture of membranes. In the absence of intrapartum antibiotic prophylaxis, 1-2% of those newborns will develop GBS EOD. Other… 
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Background Citations
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27 Citations

Updates in prevention policies of early-onset group B streptococcal infection in newborns.

Management of Infants at Risk for Group B Streptococcal Disease

TLDR
The American Academy of Pediatrics joins with the American College of Obstetricians and Gynecologists to reaffirm the use of universal antenatal microbiologic-based testing for the detection of maternal GBS colonization to facilitate appropriate administration of intrapartum antibiotic prophylaxis.

Group B Streptococcus colonization at delivery is associated with maternal peripartum infection

TLDR
GBS colonization at delivery is associated with increased risk of peripartum infection, whether this increase is due directly to invasion by GBS or whether GBS colonization isassociated with a more general vulnerability to infection remains to be determined.

Group B Streptococcal Colonization among Pregnant Women and Neonates in a Tertiary Care Hospital in South India

TLDR
Maternal GBS colonization was significantly associated with premature rupture of membrane and high maternal colonization alerts the need for GBS screening in India, andClindamycin resistance among GBS isolates questions its effectiveness as alternative therapy in penicillin allergy.

Outcomes in reported penicillin allergic mothers and neonates requiring Group B streptococcal prophylaxis: a retrospective observational cohort study

TLDR
In hospitalized obstetric patients, a PcnA label was associated with a shorter maternal course of antibiotic treatment and a longer neonatal LOS, and further prospective studies are needed to clarify the underlying reasons for these outcomes.

Regional Variation of Early-onset Neonatal Group B Streptococcal Disease Prevention Strategies in Mainland China.

TLDR
Different strategies for preventing EOGBS may be needed in different regions of mainland China, and screening strategies may be most appropriate in regions with higher attack rates, even with moderate levels of maternal GBS colonization.

Intrapartum group B Streptococcal prophylaxis and childhood weight gain

TLDR
GBS-specific IAP was associated with a modest increase in rate of early childhood weight gain and these findings highlight the need to better understand effects of intrapartum antibiotic exposure on childhood growth and support efforts to develop alternate prevention strategies.

Group B streptococcal infection of the genitourinary tract in pregnant and non-pregnant patients with diabetes mellitus: an immunocompromised host or something more?

TLDR
The evolving epidemiology, immunology, and pathophysiology of GBS urogenital infections including rectovaginal colonization during pregnancy, neonatal infections of infants exposed to DM in utero, and urinary tract infections in pregnant and non-pregnant adults in the context of DM are reviewed.

Comparison of the Panther Fusion and BD MAX Group B Streptococcus (GBS) Assays for Detection of GBS in Prenatal Screening Specimens

TLDR
The Panther Fusion GBS assay has clinical performance comparable to that of the BD MAX G BS assay but provides a faster TAT, less HoT, and higher throughput.

Middle-East OBGYN Graduate Education (MOGGE) Foundation practice guidelines: prevention of group B Streptococcus infection in pregnancy and in newborn. Practice guideline no. 02-O-20.

  • S. ShazlyA. Radwan Mostafa H Abouzeid
  • Medicine
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
  • 2021
TLDR
This guideline appraises current evidence on screening and management of GBS colonization in pregnancy particularly in low-resource settings.

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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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