Prevention of Coxiella burnetii shedding in infected dairy herds using a phase I C. burnetii inactivated vaccine.

@article{Guatto2008PreventionOC,
  title={Prevention of Coxiella burnetii shedding in infected dairy herds using a phase I C. burnetii inactivated vaccine.},
  author={Rapha{\"e}l Guatt{\'e}o and Henri Seegers and Alain Joly and François Beaudeau},
  journal={Vaccine},
  year={2008},
  volume={26 34},
  pages={4320-8}
}
The main objective of this study was to assess the efficacy of a monovalent inactivated vaccine containing phase I Coxiella burnetii to prevent Coxiella shedding in susceptible dairy cows within infected herds in comparison to a placebo. A total of 336 dairy cows and heifers, from six spontaneously infected herds, were followed over a 1-year period. Before treatment (i.e. vaccination or placebo), the C. burnetii infection status of the cows was determined on the basis on PCR results on milk… CONTINUE READING

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