Prevention of CCL4-induced liver cirrhosis by silymarin.

  title={Prevention of CCL4-induced liver cirrhosis by silymarin.},
  author={Marisa Mourelle and Pablo Muriel and L. Favari and Talita Franco},
  journal={Fundamental & clinical pharmacology},
  volume={3 3},
The efficacy of silymarin treatment in preventing biochemical and histological alterations in CCL4-induced liver cirrhosis in rats was studied. Four groups of rats were treated with: (1) CCL4; (2) mineral oil; (3) CCL4 + silymarin; and (4) silymarin. All animals were sacrificed 72 h after the end of treatments. The activities of alkaline phosphatase (alk… CONTINUE READING