Prevention by interleukin-1 of intracisternally injected thyrotropin-releasing hormone (TRH)-induced gastric mucosal lesions in rats.

Abstract

We have recently found that interleukin-1 (IL-1) acts in the central nervous system to potently inhibit gastric acid and pepsin secretion in rats. In the present study, we examined the effects of IL-1 on the development of gastric mucosal lesions induced by intracisternal (i.c.) thyrotropin-releasing hormone (TRH), a neuropeptide known to centrally… (More)

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@article{Okumura1991PreventionBI, title={Prevention by interleukin-1 of intracisternally injected thyrotropin-releasing hormone (TRH)-induced gastric mucosal lesions in rats.}, author={Toshikatsu Okumura and Akira Uehara and Shigeru Kitamori and Kunihiro Okamura and Yuichi Takasugi and Mikio Namiki}, journal={Neuroscience letters}, year={1991}, volume={125 1}, pages={31-3} }