Prevention and treatment strategies for glucocorticoid-induced osteoporotic fractures
@article{Gourlay2006PreventionAT, title={Prevention and treatment strategies for glucocorticoid-induced osteoporotic fractures}, author={M. Gourlay and N. Franceschini and Yevgeniy Sheyn}, journal={Clinical Rheumatology}, year={2006}, volume={26}, pages={144-153} }
Glucocorticoids are the most common cause of drug-related osteoporosis. We reviewed current evidence on risk factors for glucocorticoid-induced osteoporosis (GIOP) and prevention and treatment of GIOP-related fractures. Guidelines for GIOP management published since 2000 were also reviewed. Significant bone loss and increased fracture risk is seen with daily prednisone doses as low as 5 mg. Alternate-day glucocorticoid therapy can lead to similar bone loss. No conclusive evidence exists for a… CONTINUE READING
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