Prevention and treatment of acute graft-versus-host disease: the old and the new. A report from The Eastern Cooperative Oncology Group (ECOG)

@article{Lazarus1997PreventionAT,
  title={Prevention and treatment of acute graft-versus-host disease: the old and the new. A report from The Eastern Cooperative Oncology Group (ECOG)},
  author={H D Lazarus and G B Vogelsang and J K Rowe},
  journal={Bone Marrow Transplantation},
  year={1997},
  volume={19},
  pages={577-600}
}
There have been many advances in the prevention and treatment of GVHD, including cyclosporine, FK506, and combination therapies. This syndrome, however, continues to account for significant morbidity and mortality after allogeneic transplantation. With the expanded use of matched unrelated as well as mismatched related donors, the increase in incidence and severity of GVHD poses a new clinical challenge. Many of the newer agents discussed in this paper may have a role in the future as therapy… CONTINUE READING
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