Prevention and elimination of heart arrhythmias by adaptation to intermittent high altitude hypoxia.

@article{Meerson1987PreventionAE,
  title={Prevention and elimination of heart arrhythmias by adaptation to intermittent high altitude hypoxia.},
  author={Felix Z. Meerson and Elena E. Ustinova and Ehte Orlova},
  journal={Clinical cardiology},
  year={1987},
  volume={10 12},
  pages={783-9}
}
It was shown that adaptation to intermittent hypoxia in altitude chamber prevented the poststress fall of the electrical threshold of heart fibrillation. In acute ischemia, the number of fibrillation episodes and the death rate of preadapted animals were 2-3 fold lower than in controls. The adaptation to hypoxia resulted in a significant increase in concentration of opioid peptide beta-endorphin in adrenal glands while stress-induced changes in beta-endorphin in brain structures of adapted… CONTINUE READING