Prevention and Epidemiology Genomic Aberrations Occurring in Subsets of Serrated Colorectal Lesions but not Conventional Adenomas

Abstract

A subset of aggressive colorectal cancers exhibit BRAF mutation, MLH1 methylation, and a CpG island methylator phenotype (CIMP), but precursors are poorly established. In this study, we determined the status of these markers in colorectal polyps and evaluated associated risk factors. The study included 771 polyp cases and 1,027 controls who were ages 24 to… (More)

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Cite this paper

@inproceedings{BurnettHartman2013PreventionAE, title={Prevention and Epidemiology Genomic Aberrations Occurring in Subsets of Serrated Colorectal Lesions but not Conventional Adenomas}, author={Andrea N. Burnett-Hartman and Polly A Newcomb and John D. Potter and Michael N. Passarelli and Amanda I. Phipps and Michelle A. Wurscher and W. Mack Grady and Lee-Ching Zhu and Melissa P. Upton and Karen W. Makar}, year={2013} }