Preventing the development of chronic pain after orthopaedic surgery with preventive multimodal analgesic techniques.

@article{Reuben2007PreventingTD,
  title={Preventing the development of chronic pain after orthopaedic surgery with preventive multimodal analgesic techniques.},
  author={Scott S. Reuben and Asokumar Buvanendran},
  journal={The Journal of bone and joint surgery. American volume},
  year={2007},
  volume={89 6},
  pages={1343-58}
}
The prevalences of complex regional pain syndrome, phantom limb pain, chronic donor-site pain, and persistent pain following total joint arthroplasty are alarmingly high. Central nervous system plasticity that occurs in response to tissue injury may contribute to the development of persistent postoperative pain. Many researchers have focused on methods to prevent central neuroplastic changes from occurring through the utilization of preemptive or preventive multimodal analgesic techniques… CONTINUE READING

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