Preventing peritoneal membrane fibrosis in peritoneal dialysis patients.

  title={Preventing peritoneal membrane fibrosis in peritoneal dialysis patients.},
  author={Qin Hai Zhou and M Auxiliadora Bajo and Gloria del Peso and Xueqing Yu and Rafael Selgas},
  journal={Kidney international},
  volume={90 3},
Long-term peritoneal dialysis causes morphologic and functional changes in the peritoneal membrane. Although mesothelial-mesenchymal transition of peritoneal mesothelial cells is a key process leading to peritoneal fibrosis, and bioincompatible peritoneal dialysis solutions (glucose, glucose degradation products, and advanced glycation end products or a combination) are responsible for altering mesothelial cell function and proliferation, mechanisms underlying these processes remain largely… CONTINUE READING
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