Preventing oxidative stress in rats with aldosteronism by calcitriol and dietary calcium and magnesium supplements.

@article{Goodwin2006PreventingOS,
  title={Preventing oxidative stress in rats with aldosteronism by calcitriol and dietary calcium and magnesium supplements.},
  author={Kayla D Goodwin and Yao Sun and Karl T. Weber and Syamal K. Bhattacharya and Robert A. Ahokas and Ivan Gerling},
  journal={The American journal of the medical sciences},
  year={2006},
  volume={332 2},
  pages={
          73-78
        }
}
BACKGROUND Prominent features of the clinical syndrome of congestive heart failure (CHF) include aldosteronism and the presence of oxidative stress. Secondary hyperparathyroidism (SHPT) accompanies aldosteronism due to increased urinary and fecal excretion of Ca. SHPT accounts for intracellular Ca overloading of diverse cells, including peripheral blood mononuclear cells (PBMC), and the appearance of oxidative stress. Parathyroidectomy or a Ca channel blocker each prevent these responses… CONTINUE READING
BETA

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