Preventing drug-resistant tuberculosis with a fixed dose combination of isoniazid and rifampin.

@article{Moulding2004PreventingDT,
  title={Preventing drug-resistant tuberculosis with a fixed dose combination of isoniazid and rifampin.},
  author={Thomas S Moulding and Hung Q. Le and D Rikleen and Peter Davidson},
  journal={The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease},
  year={2004},
  volume={8 6},
  pages={743-8}
}
SETTING Los Angeles County Department of Health Services. OBJECTIVE To determine how well a self-administered fixed dose combination of isoniazid and rifampin (CombinedHR) prevents acquired drug resistance to Mycobacterium tuberculosis despite treatment interruptions. DESIGN Self-administered CombinedHR was given to approximately 75% of patients and directly observed therapy or separate drugs to 25%. Three quarters of the patients completed the prescribed treatment. We determined 1) how… CONTINUE READING

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