Preventing and Managing Drug-Induced Anaphylaxis

  title={Preventing and Managing Drug-Induced Anaphylaxis},
  author={Kerry L. Drain and Gerald W. Volcheck},
  journal={Drug Safety},
Drug-induced anaphylaxis and anaphylactoid reactions have increased in frequency with more widespread use of pharmaceutical agents. Anaphylaxis is a systemic, severe immediate hypersensitivity reaction caused by immunoglobulin (Ig) E-mediated immunological release of mediators of mast cells and basophils. An anaphylactoid reaction is an event similar to anaphylaxis but is not mediated by IgE.The incidence of anaphylactic or anaphylactoid reactions differs amongst classes of medications… 

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