Prevalent role of Akt and ERK activation in cardioprotective effect of Ca2+ channel- and beta-adrenergic receptor blockers

@article{Kovcs2008PrevalentRO,
  title={Prevalent role of Akt and ERK activation in cardioprotective effect of Ca2+ channel- and beta-adrenergic receptor blockers},
  author={Krisztina Kov{\'a}cs and Katalin Hant{\'o} and Zita Bognar and Antal Tapodi and Eszter Katalin Bogn{\'a}r and Gyongyi N. Kiss and Al{\'i}z Szab{\'o} and G{\'a}bor Rappai and Tam{\'a}s Kiss and Bal{\'a}zs Sumegi and Ferenc Gallyas},
  journal={Molecular and Cellular Biochemistry},
  year={2008},
  volume={321},
  pages={155-164}
}
We studied cardioprotective as well as Akt and extracellular signal-activated kinase (ERK) activating effect of a Ca2+ antagonist and a beta-adrenergic receptor blocker during ischemia-reperfusion, and compared these properties of the substances with that of a poly(ADP-ribose) polymerase (PARP) inhibitor used as a positive control throughout the experiments… CONTINUE READING