Prevalent hypertension and stroke in the Sleep Heart Health Study: association with an ECG-derived spectrographic marker of cardiopulmonary coupling.

@article{Thomas2009PrevalentHA,
  title={Prevalent hypertension and stroke in the Sleep Heart Health Study: association with an ECG-derived spectrographic marker of cardiopulmonary coupling.},
  author={Robert Joseph Thomas and Matthew D. Weiss and Joseph E. Mietus and Chung-Kang Peng and Ary L. Goldberger and Daniel J. Gottlieb},
  journal={Sleep},
  year={2009},
  volume={32 7},
  pages={897-904}
}
STUDY OBJECTIVES The electrocardiogram (ECG)-based sleep spectrogram generates a map of cardiopulmonary coupling based on heart rate variability and respiration derived from QRS amplitude variations. A distinct spectrographic phenotype, designated as narrow-band elevated low frequency coupling (e-LFC(NB)), has been associated with central apneas and periodic breathing and predicts sleep laboratory failure of continuous positive airway pressure therapy. This study assesses, at a population level… CONTINUE READING

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