Prevalence of serum antibodies against the p53 tumor suppressor gene protein in various cancers.

@article{Angelopoulou1994PrevalenceOS,
  title={Prevalence of serum antibodies against the p53 tumor suppressor gene protein in various cancers.},
  author={Katerina Angelopoulou and Eleftherios P Diamandis and Donald J. A. Sutherland and John A. Kellen and Peter S Bunting},
  journal={International journal of cancer},
  year={1994},
  volume={58 4},
  pages={480-7}
}
We have developed 2 new quantitative methods for measuring anti-p53 antibodies in human serum. Using these methods we analyzed 1,392 sera from patients with various malignancies and 230 sera from individuals without malignancy. Highest prevalence of anti-p53 antibodies was associated with ovarian and colon cancers (15%), followed by lung (8%) and breast (5%) cancers. Prevalence in other malignancies was lower (< 4%). In hospitalized patients and apparently healthy individuals, prevalence was… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 78 extracted citations

Similar Papers

Loading similar papers…