Prevalence of serologic reactivity against four strains of mouse mammary tumour virus among US women with breast cancer

@article{Goedert2006PrevalenceOS,
  title={Prevalence of serologic reactivity against four strains of mouse mammary tumour virus among US women with breast cancer},
  author={James Jerome Goedert and Charles S. Rabkin and Susan R Ross},
  journal={British Journal of Cancer},
  year={2006},
  volume={94},
  pages={548 - 551}
}
Mouse mammary tumour virus (MMTV) causes breast cancer in mice, and MMTV-specific antibodies develop to high titers among mice infected as adults. Whether MMTV or a related virus infects humans is uncertain, because MMTV DNA sequences have been detected inconsistently and because serologic methods have varied widely. The current study used immunoblot and immunoprecipitation with four strains of MMTV (RIII, FM, C3H, and LA) to detect specific antibodies in 92 sera from US women with breast… CONTINUE READING
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