Prevalence of primary sclerosing cholangitis in patients with ulcerative colitis and the risk of developing malignancies. A large prospective study.

@article{Terg2008PrevalenceOP,
  title={Prevalence of primary sclerosing cholangitis in patients with ulcerative colitis and the risk of developing malignancies. A large prospective study.},
  author={Ruben A Terg and Alicia Mar{\'i}a Sambuelli and Emma Coronel and Juan Mazzuco and Mariano Cartier and Silvia M{\'o}nica Negreira and Alberto Mu{\~n}oz and An{\'i}bal H{\'e}ctor Gil and Carlos M{\'i}guez and Sergio Pablo Huernos and Gustavo Bueno Romero and Silvina Goncalvez and Diana Levi and Raquel Abecasis},
  journal={Acta gastroenterologica Latinoamericana},
  year={2008},
  volume={38 1},
  pages={26-33}
}
BACKGROUND/AIM primary sclerosing cholangitis (PSC) is associated with ulcerative colitis (UC) and seems to be a risk factor for colon cancer. However, taking into account that no data are available in South American population, we analyzed the prevalence of PSC in 1,333 patients with UC and the risk for developing colon cancer. MATERIAL patients with persistent increases of alkaline phosphatase were studied by cholangiography and liver biopsy. To assess the risk of colon cancer, each patient… CONTINUE READING
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