Prevalence of mutations of the NOD2/CARD15 gene and relation to phenotype in Spanish patients with Crohn disease.

@article{Mendoza2003PrevalenceOM,
  title={Prevalence of mutations of the NOD2/CARD15 gene and relation to phenotype in Spanish patients with Crohn disease.},
  author={Juan Lu{\'i}s Mendoza and Laura S. Murillo and Laura Lorente Fern{\'a}ndez and Amado Salvador Pe{\~n}a and Raquel Lana and Elena Urcelay and Dulce Maria Cruz-Santamaria and Emilio G{\'o}mez de la Concha and Manuel D{\'i}az-Rubio and Julio Garc{\'i}a-Paredes},
  journal={Scandinavian journal of gastroenterology},
  year={2003},
  volume={38 12},
  pages={1235-40}
}
BACKGROUND We assessed the prevalence of R702W, G908R, and L1007fs coding mutations in the NOD2/CARD15 gene and the genotype-phenotype relation in Spanish patients with Crohn disease. METHODS A cohort of 204 unrelated patients with Crohn disease and 140 healthy controls were studied. The phenotype was established before commencement of genotyping. Genotyping of the R702W, G908R, and L1007fs gene polymorphisms of NOD2/CARD15 was performed by two independent laboratories using different… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 33 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 35 references

Similar Papers

Loading similar papers…