Prevalence of localized rearrangements vs. transpositions among events induced by Drosophila P element transposase on a P transgene.

@article{Delattre1995PrevalenceOL,
  title={Prevalence of localized rearrangements vs. transpositions among events induced by Drosophila P element transposase on a P transgene.},
  author={Marie Delattre and Dominique Anxolab{\'e}h{\`e}re and Dario Coen},
  journal={Genetics},
  year={1995},
  volume={141 4},
  pages={1407-24}
}
We have studied P transposase-induced events on a P[w] transgene, P[wd1], harboring the whole white gene with a 3.44-kb direct duplication of its 5' regulatory sequences (containing the ZESTE-binding region, ZBR). We have recovered mutations leading to an increase or a decrease of zeste1 repression, generally as the consequence of modifications of number of ZBR in close physical proximity and/or jumps to other sites. We describe mutants displaying deletions of the original duplicated sequence… CONTINUE READING

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