Prevalence of known mutations in the MEFV gene in a population screening with high rate of carriers

@article{Ozdemir2010PrevalenceOK,
  title={Prevalence of known mutations in the MEFV gene in a population screening with high rate of carriers},
  author={Ozt{\"u}rk Ozdemir and Ilhan Sezgin and Hande Kucuk Kurtulgan and Ferhan Candan and Binnur Koksal and Haldun Sumer and Dilara {\^I}çağasioğlu and Atilla Uslu and Fazilet Yildiz and Sulhattin Arslan and Selma G{\"o}kt{\"u}rk Çetinkaya and Senol Çitli and Zekeriya Oztemur and Mansur Kayataş},
  journal={Molecular Biology Reports},
  year={2010},
  volume={38},
  pages={3195-3200}
}
The Familial Mediterranean Fever (FMF) shows an autosomal recessive pattern of inheritance and affects certain ethnic groups. Disease is caused by mutations in MEFV gene and more than 180 mutations have been defined in affected individuals. Current study aimed to determine the frequency-type of the mutations for MEFV gene in Sivas—middle Anatolian city. The cohort was composed of 3340 patients. MEFV gene mutations were studied by multiplex PCR based reverse hybridization stripAssay method… CONTINUE READING
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The spectrum of FMF mutations and genotypes in the referrals to molecular genetics laboratory at Kirikkale University in Turkey

A Gunel-Ozcan, DB Sayin, +3 authors C Ensari
  • Mol Biol Rep
  • 2009

Familial Mediterranean fever gene mutations in the Southeastern region of Turkey and their phenotypical features.

  • Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis
  • 2008