Prevalence of homozygosity for the deleted alleles of glutathione S-transferase mu (GSTM1) and theta (GSTT1) among distinct ethnic groups from Brazil: relevance to environmental carcinogenesis?

@article{Arruda1998PrevalenceOH,
  title={Prevalence of homozygosity for the deleted alleles of glutathione S-transferase mu (GSTM1) and theta (GSTT1) among distinct ethnic groups from Brazil: relevance to environmental carcinogenesis?},
  author={Valder R Arruda and C E Grignolli and Marilda de Souza Gonçalves and Manoel do Carmo Pereira Soares and Raimundo C Menezes and Sara T. O. Saad and Fernando F. Costa},
  journal={Clinical genetics},
  year={1998},
  volume={54 3},
  pages={210-4}
}
Environmental related diseases due to occupational carcinogens and toxic substances are a serious problem particularly in developing countries. The glutathione S-transferase system is fundamental for the detoxification of numerous carcinogens and mutagens. The individual inherited susceptibility to chemical carcinogenesis due to glutathione S-transferase mu (GSTM1) and theta (GSTT1) varies significantly among distinct ethnic groups. In this study we determined the prevalence of the null… CONTINUE READING
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