Prevalence of factor V gene mutation amongst myocardial infarction patients and healthy controls is higher in Sweden than in other countries.

@article{Holm1996PrevalenceOF,
  title={Prevalence of factor V gene mutation amongst myocardial infarction patients and healthy controls is higher in Sweden than in other countries.},
  author={Johan Holm and Bengt Z{\"o}ller and E Berntorp and Leif Rw Erhardt and Bj{\"o}rn Dahlb{\"a}ck},
  journal={Journal of internal medicine},
  year={1996},
  volume={239 3},
  pages={221-6}
}
OBJECTIVE Haemostatic imbalance may be an aetiological factor in the development of acute coronary syndromes. Inherited resistance to activated protein C (APC) is a common disorder associated with hypercoagulability and lifelong risk of venous thrombosis. APC resistance is due to a single mutation in the gene coding for coagulation factor V (FV:Q506). To test the importance of the FV:Q506 mutation in premature myocardial infarction (MI), its prevalence was investigated in Swedish patients with… CONTINUE READING

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