Prevalence of coeliac disease in patients with sarcoidosis

@article{Rutherford2004PrevalenceOC,
  title={Prevalence of coeliac disease in patients with sarcoidosis},
  author={R. Rutherford and M. Brutsche and M. Kearns and M. Bourke and F. Stevens and J. Gilmartin},
  journal={European Journal of Gastroenterology \& Hepatology},
  year={2004},
  volume={16},
  pages={911-915}
}
Objective Susceptibility to sarcoidosis and coeliac disease has been linked to the class II haplotype HLA-DR3, DQ2, and an association between the two disorders has been suggested. As a pilot study, we have sought to determine the prevalence of coeliac disease in a cohort of Irish patients with sarcoidosis. Design Prospective, case-controlled study. Methods One hundred and two sarcoid patients (47 males, 55 females) from the west of Ireland and 105 (52 males, 53 females) healthy, ethnically… Expand
Screening of Celiac Disease in Patients With Sarcoidosis?
TLDR
A 35-year-old woman who was diagnosed with biopsyproven sarcoidosis developed a complex clinical course over time, and over time developed other symptoms such as nonspecific dermatitis, hair loss, and oral ulcers. Expand
Sarcoidosis in Patients with Celiac Disease
TLDR
In this cohort of patients with celiac disease, there was a significantly increased risk of sarcoidosis when compared with the American white population, which further strengthens prior associations that have been made suggesting a shared mechanism behind the etiologies of celiac health. Expand
Coeliac disease and risk of tuberculosis: a population based cohort study
TLDR
CD is associated with TB and may be due to malabsorption and lack of vitamin D in persons with CD, which should be investigated for CD. Expand
A case series in patients with enteropathy and granulomatous diseases
TLDR
The HLA-DR3/DQ2 haplotype was confirmed in both celiac patients, hence confirming previous data of linkage disequilibrium as a cause for disease association and determining the HLA status in patients with complex autoimmune associations might help classifying involved disease entities. Expand
Coeliac disease associated with sarcoidosis and antiphospholipid syndrome: A case report
TLDR
A 27-year-old Tunisian woman with a history of non-explored superficial vein thrombosis and 4 successive miscarriages is described, who was explored for abdominal pain, vomiting, hypercalcemia, hepatic cytolyses and cholestasis and was complicated later with pancreatitis and anterior uveitis. Expand
Morbidity and Mortality Associated with Celiac Disease
TLDR
It is important that comorbidities are identified; otherwise, symptoms may be falsely attributed to CD in relapse rather than prompt a search for another diagnosis, and in a patient with an established diagnosis, CD may be overlooked. Expand
Positive serum antigliadin antibodies without celiac disease in the elderly population: does it matter?
TLDR
Although AGA positivity is of clinical relevance only in a subset of elderly people, it seems to be related to rheumatoid arthritis and depression, both conditions linked to celiac disease. Expand
Immune-mediated and chronic inflammatory disease in people with sarcoidosis: disease associations in a large UK database
TLDR
This study adds epidemiological evidence to information from clinical reports that there is a connection between sarcoidosis and other immune-mediated and chronic inflammatory diseases. Expand
Celiac Disease and Autoimmune-Associated Conditions
TLDR
General practitioners and other specialists must remember that CD may debut with extraintestinal manifestations, and associated illnesses may appear both at the time of diagnosis and throughout the evolution of the disease. Expand
Sarcoidosis and coeliac disease: do not forget the association!
TLDR
CD should be promptly sought in all patients with sarcoidosis and a unexplained iron deficiency anaemia, before performing more invasive diagnostic tests, as was the case in a 70-year-old woman. Expand
...
1
2
3
4
...

References

SHOWING 1-10 OF 37 REFERENCES
"The sarcoidosis map": a joint survey of clinical and immunogenetic findings in two European countries.
TLDR
The concept that immunogenetic background may at least partly account for the clinical heterogeneity of sarcoidosis is supported, as data obtained in independent studies in two European populations (Italian and Czech) seem to support that. Expand
HLA-DR predicts the prognosis in Scandinavian patients with pulmonary sarcoidosis.
TLDR
HLA class II typing is a valuable tool in predicting the outcome of the disease in Scandinavian sarcoidosis patients and enabled a subgrouping into two categories with significantly different clinical courses, even in patients with clinical manifestations normally associated with good prognosis. Expand
Altered gastrointestinal immune response in sarcoidosis.
TLDR
Findings suggest that in patients with sarcoidosis, there is an altered gastrointestinal mucosal immune response, accompanied in about 40% of patients by specific sensitisation to wheat protein. Expand
Prevalence of Celiac disease among children in Finland.
TLDR
The presence of serum tissue transglutaminase and endomysial autoantibodies is predictive of small-bowel abnormalities indicative of celiac disease and there is a good correlation betweenAutoantibody positivity and specific HLA haplotypes. Expand
Endomysial antibody: is it the best screening test for coeliac disease?
TLDR
It is concluded that the endomysial antibody is superior to other current antibody tests and should be used in preference for the diagnosis of coeliac disease. Expand
Serological screening of coeliac disease: choosing the optimal procedure according to various prevalence values.
TLDR
Antigliadin antibodies are useful to screen for asymptomatic coeliac disease in non-hospital communities if antiendomysium anti-bodies are used as a confirmation test: the latter is reasonable valid alternative to duodenal biopsy. Expand
Antiendomysium versus antigliadin antibodies in screening the general population for coeliac disease.
TLDR
The EMA protocol is superior to the AGA protocol for mass screening of coeliac disease because of higher sensitivity, decreased need for intestinal biopsy, and possibility to detect potential cases of coediac disease. Expand
HLA-B8/DR3 in sarcoidosis. Correlation to acute onset disease with arthritis.
TLDR
The strong association between the acute, prognostically beneficial manifestation of sarcoidosis and HLA-DR3 might partly be related to the presence of circulating immune complexes in acute sarCOidosis as well as to an immunogenetically determined handling of a postulated etiological antigen. Expand
Variation in immunoglobulin levels and circulating immune complexes in sarcoidosis. Correlation with extent of disease and duration of symptoms.
TLDR
The presence of circulating immune complexes reacting with conglutinin was strongly associated with a recent symptomatic onset of sarcoidosis; they were more prevalent in patients with BHL and erythema nodosum and polyethylene glycol precipitable immunoglobulins were associated with long-standing active disease and with neurologic involvement. Expand
Malignancy in coeliac disease--effect of a gluten free diet.
TLDR
The results indicate that for coeliac patients who have taken a GFD for five years or more the risk of developing cancer over all sites is not increased when compared with the general population, and give further support for advising all patients to adhere to a strict G FD for life. Expand
...
1
2
3
4
...