Prevalence of bronchial hyperresponsiveness among HIV-infected men.

  title={Prevalence of bronchial hyperresponsiveness among HIV-infected men.},
  author={Charles Poirier and Neil Inhaber and Richard Lalonde and Pierre Ernst},
  journal={American journal of respiratory and critical care medicine},
  volume={164 4},
HIV infection is associated with immune dysregulation primarily affecting T-cell function, whereas asthma is related to excessive T-cell activity. We compared the prevalence of asthma and related conditions among adult seropositive men with the prevalence among men of similar age drawn from the general population. Seropositive men had a significantly more frequent occurrence of wheezing (54.4 versus 21.2%), bronchial hyperresponsiveness (BHR) to methacholine (26.2 versus 14.4%), and an elevated… CONTINUE READING