Prevalence of abnormal levels of serum tumour markers in elderly people.

@article{Lpez1996PrevalenceOA,
  title={Prevalence of abnormal levels of serum tumour markers in elderly people.},
  author={L L{\'o}pez and Valent{\'i}n del Villar and Marco Ulla and F Fernandez and Louis A. Fernandez and Isabel Santos and Lorenzo Rabad{\'a}n and Maria Rosario Mercado Gutierrez},
  journal={Age and ageing},
  year={1996},
  volume={25 1},
  pages={
          45-50
        }
}
The study was conducted to evaluate the prevalence of abnormal levels of several serum tumour markers in an institutionalized elderly population. Serum tumour markers assay of carcinoembryonic antigen (CEA), the carbohydrate antigens CA 19-9, CA 72-4 and CA 15-3 (Enzymun-test, Boehringer Mannheim GmbH Diagnostic), alpha-fetoprotein (AFP) and prostate specific antigen (PSA) (Abbot Diagnostic Division) were performed in 228 unselected, institutionalized elderly subjects, whose mean age (SD) was… 
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25 Citations

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Evaluation of serum tumour markers concentrations in patients with homozygous β-thalassaemia in relation to demographical, clinical and biochemical parameters
TLDR
The results indicate that CA 15.3 seems to be an unreliable marker of occult malignancy in patients with β-thalassaemia, and more studies are needed to support these preliminary results.
A Prospective Study of Serum Carcinoembryonic Antigen in Patients with Newly Diagnosed Colorectal Cancer and Healthy Individuals
TLDR
Comparing the effect of smoking, age, sex and on elevated levels of carcinoembryonic antigen (CEA) among the healthy individuals and in patients with newly diagnosed colorectal cancer indicated that even a very high CEA level should not be considered by itself as evidence of cancer.
Standard serum concentrations and normal fluctuations of CEA, CA 50 and CA 242 during twelve months in men and women aged 60-64 years without malignant disease.
TLDR
Serum concentrations of CEA, CA 50, and CA 242 were higher in this study than previously reported, probably because the subjects were older than in other reports, and the fluctuations were small.
Factors influencing serum concentration of CA125 and CA15-3 in Iranian healthy postmenopausal women
TLDR
Serum CA125 is imperative indicator for malignancies of the ovary; however, personal and medical factors influence its serum level, and a fair interpretation of results must be due to an accurate attention to the individual characteristics.
Increased Serum CA-15.3 Levels in Patients with Megaloblastic Anemia due to Vitamin B12 Deficiency
TLDR
Serum CA-15.3 shows an aberrant increase in untreated patients with pernicious anemia, which is reversed after the correction of the anemia), and may be released by the apoptosing bone marrow megaloblastic erythroblasts.
Kinetics of serum tumor marker concentrations and usefulness in clinical monitoring.
TLDR
This report reviews the interest of determining kinetic parameters for prostate-specific antigen, human chorionic gonadotropin, alpha-fetoprotein, carcinoembryonic antigen, cancer antigen (CA) 125, and CA 15-3 and finds this kinetic approach could be of interest to optimize patient management.
Elevated tumour marker: an indication for imaging?
TLDR
‘Elevated tumour marker’, in the absence of a known underlying malignancy, should not be considered an independent indication for imaging and can prompt further unnecessary investigations including imaging.
Reference Levels of the Tumor Markers Carcinoembryonic Antigen, the Carbohydrate Antigens 19-9 and 72-4, and Cytokeratin Fragment 19 Using the ®Elecsys Relecsys 1010 Analyzer in a Normal Population in Kuwait. The Importance of the Determination of Local Reference Levels
TLDR
Because the 95% reference levels of CEA, CA 19-9, CA 72-4 and CYFRA 21-1 using the Elecsys Relecsys 1010 system were wanted to use in a prospective study in gastrointestinal cancer patients, they were examined in the normal population in Kuwait.
Estimation of probability of malignancy using a logistic model combining physical examination, ultrasound, serum CA 125, and serum CA 72-4 in postmenopausal women with a pelvic mass: an international multicenter study.
TLDR
The addition of serum CA 72-4 to the combination of pelvic examination, ultrasound, and serum CA 125 leads to an improved discrimination between malignant and benign pelvic masses.
Role of Ca 15-3 in patients with biochemically suspected prostate cancer and multiple negative ultrasound-guided prostate biopsies
TLDR
It is hypothesized that Ca 15-3, as a specific tumor marker, could be an interesting and inexpensive second step diagnostic tool for PCa in patients with borderline PSA and multiple negative prostate biopsies, as it could indicate whether a repeated biopsy should be performed in a short time, having excluded other concomitant tumors.
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TLDR
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